| Science/Configuration Option | CAMx v6.10 | CMAQ v5.0.2 | Details |
| Nesting | One-way, Two-way, and Flexi-nest | One-way | |
| Meteorology | WRF-CAMx (Offline) | | |
| Emissions | SMOKE (Offline) | | |
| Plume-in grid | GREASD;GREASD (simple chemistry); IRON (complex chemistry) | | |
| Gas-Phase Chemistry | CB05, CB6, CB6r2, CB6 with iodine; Mechanism 10 (user defined); SAPRC99 | | |
| Gas-Phase Chemistry Solver | EBI, IEH, LSODE/Gear | | |
| Photolysis | TUV | | |
| Aqueous Chemistry | RADM-AQ | | |
| Aerosol Chemistry | Two-mode course/fine scheme (modal) and multi-sectional CMU scheme (sectional) | | |
| Aerosol Thermodynamics | ISOROPEA | | |
| Secondary Organic Aerosols | SOAP | | |
| Other Chemistry | Multi-phase Hg; Surface Chemistry/Re-emission Model | | |
| Dry Deposition | 11 category LULC (Wesely/Slinn), 26 category LULC (Zhang) | | |
| Wet Deposition | Scavenging model | | |
| Horizontal Advection | PPM, Bott | | |
| Horizontal Diffusion | K-theory 1st order closure | | |
| Vertical Advection | Implicit backward-Euler (time) hybrid centered/upstream (space) solver | | |
| Vertical Diffusion | K-theory, ACM2 | | |
| Integration Time Step | | | |
| Multi-Processing | OpenMP; MPI; Hybrid OpenMP-MPI | | |